Giuseppe De Luca (25 December 1876 – 26 August 1950), was a famous Italian baritone who achieved his greatest triumphs at the New York Metropolitan Opera. He notably created roles in the world premieres of two operas by Giacomo Puccini: Sharpless in Madama Butterfly (at La Scala, Milan, 1904) and the title role in Gianni Schicchi (Metropolitan Opera, 1918).
De Luca was born in Rome, the son of a blacksmith, and sang in church choirs as a boy. After his voice broke, a wealthy patron paid for him to have singing lessons at the Rome Conservatory, where he studied with two top-class pedagogues, Venceslao Persichini (who also taught De Luca's fellow baritone stars Mattia Battistini and Titta Ruffo) and Antonio Cotogni. He made his operatic debut at Piacenza in 1897, singing Valentin in Gounod's Faust. His debut proved a success and he was invited to sing at a string of more important venues.

He appeared at Italy's foremost opera house, La Scala, Milan, from 1902 to 1910, and made his London debut at the Royal Opera House, Covent Garden, in 1907.
Subsequently, De Luca moved to America where he became a leading baritone at the Metropolitan Opera for 20 years, from 1915 to 1935. (He returned briefly to the Met in 1939–1940.) His first appearance at that house was on 25 November 1915, as Figaro in The Barber of Seville with Frieda Hempel as Rosina and Giacomo Damacco as Count Almaviva, with Gaetano Bavagnoli conducting.

After his retirement, he taught voice at the Juilliard School. He died in New York City at the age of 73.