In 2004 at the age of 19, Green emailed Lou Schuler, former fitness director of Men's Health magazine. Green told Schuler he wanted his job and asked for advice on writing and publishing.[8] Schuler became Green's first of many mentors who helped Green along in his career.

A former personal trainer, Green began to focus more on writing and in 2006, Green created his blog, The Nate Green Experience.[9] Green later became a contributing editor to T-Nation.[10] He left his position with T-Nation in 2010 and joined Precision Nutrition where he currently works as a writer and marketing strategist.[11]

In 2010, Green also helped author Tim Ferriss with research for his book The 4-Hour Body