1963年7月8日出生于阿拉斯加南部的安克雷奇。90年代早期来到纽约，就读于纽约大学电影学院。一个偶然的机会琼在当地一家小酒吧中演唱了爵士歌后比莉-郝乐迪的名曲“上帝保佑孩子”，自此人生的轨迹完全被改变。她开始从事音乐事业，模仿自己所喜欢的埃特-詹姆斯以及蕾-查尔斯等人进行表演。最初奥斯本不愿受大唱片公司的摆布，自己成立了厂牌“女性欢呼”(Womanly Hips)，并推出《灵魂展示》(Soul Show)这样一张唱片，还与其他艺人一起举办音乐会。1995年，她终于认识到商业合作的重要性，就与Mercury公司签约，第二张《意味》(Relish)由此发行。经过将近一年时间的等待，公众发觉了这张专辑的价值，单曲《我们中的一个》(One Of Us)成为排行榜首，并使她在1996和1997年获得诸多格莱美奖提名。
琼-奥斯本是一名非常具有社会责任感的女艺人，音乐创作之余，经常参与到一些认为重要的公众事业当中去。选举、投票、节育、妇女权益都是她感兴趣的主题。
Singer Joan Osborne was born on July 8, 1962, in the town of Anchorage, KY, but it wasn't until relocating to New York City in the early '90s (to study at NYU's film school) that she began to take a singing career seriously after singing Billie Holiday's classic "God Bless the Child" at a local bar's open mic night. In addition to Holiday, Osborne looked to such legendary vocalists as Etta James and Ray Charles as role models, as the up-and-coming singer decided not to cater to major record companies and formed her own label, Womanly Hips, which resulted in such releases as 1992's in-concert Soul Show, among others. But eventually Osborne decided to sign on with a major label, Mercury, which in turn issued the singer's next release, Relish, in March 1995. The album proved to have a long life, as almost a year after its initial release the track "One of Us" became a massive MTV and radio smash, camping out at the number one spot on the U.S. singles chart for two weeks, and Relish eventually racked up sales of three million copies. Further tracks ("Right Hand Man" and "St. Teresa") failed to match the success of Osborne's first hit, but the singer still managed to connect with a large and appreciative audience, especially during touring as part of the 1997 edition of Sarah McLachlan's Lilith Fair tour. Osborne also received numerous Grammy nominations in both 1996 and 1997.
Producing a worthy follow-up to Relish proved to be a time-consuming challenge for Osborne. Mercury tried to buy some time by issuing a compilation release, Early Recordings (which collected the early releases Live at Delta '88 and Blue Million Miles). In the meantime, Osborne focused on supporting a few groups/causes she felt strongly about, such as Rock the Vote and Planned Parenthood (eventually being named an honorary member of Planned Parenthood's Board of Advocates), in addition to covering "I'm Just a Bill" as a duet with Isaac Hayes on the 1998 Schoolhouse Rocks the Vote! benefit album. She also studied briefly with late Qawwali master Nusrat Fateh Ali Khan and performed alongside such notables as Stevie Wonder, Melissa Etheridge, Taj Mahal, Luciano Pavarotti, Spearhead, Bob Dylan, and the Chieftains. September 2000 finally saw the release of Osborne's next all-new studio album, titled Righteous Love, which failed to match its predecessor's commercial success and sunk from sight shortly after release. She bounced back in 2002 with How Sweet It Is, a collection of covers that leaned heavily on classic soul and R&B tunes from the 1960s and '70s. A career retrospective, One of Us, followed in 2005. Vanguard picked her up shortly after this, and Osborne released her first full-length on that label, a country-tinged effort called Pretty Little Stranger, in 2006. It was followed in 2007 by Breakfast in Bed.